The National Institutes of Health published a paper by Khoury et al in 2010 on Substance Use Disorder (SUD) and childhood trauama.
Exposure to traumatic experiences, especially those occurring in childhood, has been linked to substance use disorders (SUDs), including abuse and dependence. SUDs are also highly co-morbid with Posttraumatic Stress Disorder (PTSD) and other mood-related psychopathology. Most studies examining the relationship between PTSD and SUDs have examined veteran populations or patients in substance treatment programs. The present study further examines this relationship between childhood trauma, substance use, and PTSD in a sample of urban primary care patients.
Read the paper, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051362/